WEB-based GEne SeT AnaLysis Toolkit
 
Translating gene lists into biological insights...
 


User data and parameters: User data: textAreaUpload.txt, Organism: hsapiens, Id Type: ensembl_gene_stable_id, Ref Set: entrezgene, Significance Level: Top10, Statistics Test: Hypergeometric, MTC: BH, Minimum: 2

The results for each enriched gene sets are listed in this table.
For each gene set, the first row lists database name, gene set name , and corresponding gene set ID. The second row lists the following statistics:
Finally, genes in the gene set are listed. For each gene, the table lists the user uploaded ID and value (optional), Entrez ID, Ensembl Gene Stable ID, Gene symbol, and description. Ensembl Gene Stable ID and Entrez Gene ID are linked to the Ensembl and Entrez Gene databases, respectively.

Database:Transcription Target       Name:hsa_AACTTT_UNKNOWN       ID:DB_ID:1851
C=1859; O=28; E=4.09; R=6.84; rawP=2.71e-16; adjP=8.43e-14
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000164040 NA PGRMC2 progesterone receptor membrane component 2 10424 ENSG00000164040
2  ENSG00000178031 NA ADAMTSL1 ADAMTS-like 1 92949 ENSG00000178031
3  ENSG00000146021 NA KLHL3 kelch-like 3 (Drosophila) 26249 ENSG00000146021
4  ENSG00000148200 NA NR6A1 nuclear receptor subfamily 6, group A, member 1 2649 ENSG00000148200
5  ENSG00000091428 NA RAPGEF4 Rap guanine nucleotide exchange factor (GEF) 4 11069 ENSG00000091428
6  ENSG00000244405 NA ETV5 ets variant 5 2119 ENSG00000244405
7  ENSG00000076356 NA PLXNA2 plexin A2 5362 ENSG00000076356
8  ENSG00000198732 NA SMOC1 SPARC related modular calcium binding 1 64093 ENSG00000198732
9  ENSG00000169252 NA ADRB2 adrenoceptor beta 2, surface 154 ENSG00000169252
10  ENSG00000178568 NA ERBB4 v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian) 2066 ENSG00000178568
11  ENSG00000186867 NA QRFPR pyroglutamylated RFamide peptide receptor 84109 ENSG00000186867
12  ENSG00000177508 NA IRX3 iroquois homeobox 3 79191 ENSG00000177508
13  ENSG00000185436 NA IL28RA interleukin 28 receptor, alpha (interferon, lambda receptor) 163702 ENSG00000185436
14  ENSG00000163630 NA SYNPR synaptoporin 132204 ENSG00000163630
15  ENSG00000176842 NA IRX5 iroquois homeobox 5 10265 ENSG00000176842
16  ENSG00000147606 NA SLC26A7 solute carrier family 26, member 7 115111 ENSG00000147606
17  ENSG00000197467 NA COL13A1 collagen, type XIII, alpha 1 1305 ENSG00000197467
18  ENSG00000167323 NA STIM1 stromal interaction molecule 1 6786 ENSG00000167323
19  ENSG00000135914 NA HTR2B 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled 3357 ENSG00000135914
20  ENSG00000184672 NA RALYL RALY RNA binding protein-like 138046 ENSG00000184672
21  ENSG00000157680 NA DGKI diacylglycerol kinase, iota 9162 ENSG00000157680
22  ENSG00000075945 NA KIFAP3 kinesin-associated protein 3 22920 ENSG00000075945
23  ENSG00000157168 NA NRG1 neuregulin 1 3084 ENSG00000157168
24  ENSG00000162989 NA KCNJ3 potassium inwardly-rectifying channel, subfamily J, member 3 3760 ENSG00000162989
25  ENSG00000162670 NA FAM5C family with sequence similarity 5, member C 339479 ENSG00000162670
26  ENSG00000065320 NA NTN1 netrin 1 9423 ENSG00000065320
27  ENSG00000175832 NA ETV4 ets variant 4 2118 ENSG00000175832
28  ENSG00000152894 NA PTPRK protein tyrosine phosphatase, receptor type, K 5796 ENSG00000152894


Database:Transcription Target       Name:hsa_CAGGTG_V$E12_Q6       ID:DB_ID:2409
C=2450; O=30; E=5.40; R=5.56; rawP=4.56e-15; adjP=7.09e-13
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000102010 NA BMX BMX non-receptor tyrosine kinase 660 ENSG00000102010
2  ENSG00000184156 NA KCNQ3 potassium voltage-gated channel, KQT-like subfamily, member 3 3786 ENSG00000184156
3  ENSG00000143126 NA CELSR2 cadherin, EGF LAG seven-pass G-type receptor 2 (flamingo homolog, Drosophila) 1952 ENSG00000143126
4  ENSG00000170421 NA KRT8 keratin 8 3856 ENSG00000170421
5  ENSG00000146021 NA KLHL3 kelch-like 3 (Drosophila) 26249 ENSG00000146021
6  ENSG00000148200 NA NR6A1 nuclear receptor subfamily 6, group A, member 1 2649 ENSG00000148200
7  ENSG00000175206 NA NPPA natriuretic peptide A 4878 ENSG00000175206
8  ENSG00000091428 NA RAPGEF4 Rap guanine nucleotide exchange factor (GEF) 4 11069 ENSG00000091428
9  ENSG00000076356 NA PLXNA2 plexin A2 5362 ENSG00000076356
10  ENSG00000166016 NA ABTB2 ankyrin repeat and BTB (POZ) domain containing 2 25841 ENSG00000166016
11  ENSG00000198732 NA SMOC1 SPARC related modular calcium binding 1 64093 ENSG00000198732
12  ENSG00000169252 NA ADRB2 adrenoceptor beta 2, surface 154 ENSG00000169252
13  ENSG00000117595 NA IRF6 interferon regulatory factor 6 3664 ENSG00000117595
14  ENSG00000131188 NA PRR7 proline rich 7 (synaptic) 80758 ENSG00000131188
15  ENSG00000178568 NA ERBB4 v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian) 2066 ENSG00000178568
16  ENSG00000176842 NA IRX5 iroquois homeobox 5 10265 ENSG00000176842
17  ENSG00000166833 NA NAV2 neuron navigator 2 89797 ENSG00000166833
18  ENSG00000197467 NA COL13A1 collagen, type XIII, alpha 1 1305 ENSG00000197467
19  ENSG00000073737 NA DHRS9 dehydrogenase/reductase (SDR family) member 9 10170 ENSG00000073737
20  ENSG00000061918 NA GUCY1B3 guanylate cyclase 1, soluble, beta 3 2983 ENSG00000061918
21  ENSG00000157680 NA DGKI diacylglycerol kinase, iota 9162 ENSG00000157680
22  ENSG00000184672 NA RALYL RALY RNA binding protein-like 138046 ENSG00000184672
23  ENSG00000157168 NA NRG1 neuregulin 1 3084 ENSG00000157168
24  ENSG00000105737 NA GRIK5 glutamate receptor, ionotropic, kainate 5 2901 ENSG00000105737
25  ENSG00000108556 NA CHRNE cholinergic receptor, nicotinic, epsilon (muscle) 1145 ENSG00000108556
26  ENSG00000107731 NA UNC5B unc-5 homolog B (C. elegans) 219699 ENSG00000107731
27  ENSG00000164116 NA GUCY1A3 guanylate cyclase 1, soluble, alpha 3 2982 ENSG00000164116
28  ENSG00000175832 NA ETV4 ets variant 4 2118 ENSG00000175832
29  ENSG00000183091 NA NEB nebulin 4703 ENSG00000183091
30  ENSG00000152894 NA PTPRK protein tyrosine phosphatase, receptor type, K 5796 ENSG00000152894


Database:Transcription Target       Name:hsa_CTTTGA_V$LEF1_Q2       ID:DB_ID:2427
C=1208; O=17; E=2.66; R=6.39; rawP=1.18e-09; adjP=1.22e-07
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000138119 NA MYOF myoferlin 26509 ENSG00000138119
2  ENSG00000178031 NA ADAMTSL1 ADAMTS-like 1 92949 ENSG00000178031
3  ENSG00000175206 NA NPPA natriuretic peptide A 4878 ENSG00000175206
4  ENSG00000244405 NA ETV5 ets variant 5 2119 ENSG00000244405
5  ENSG00000205038 NA PKHD1L1 polycystic kidney and hepatic disease 1 (autosomal recessive)-like 1 93035 ENSG00000205038
6  ENSG00000159212 NA CLIC6 chloride intracellular channel 6 54102 ENSG00000159212
7  ENSG00000164741 NA DLC1 deleted in liver cancer 1 10395 ENSG00000164741
8  ENSG00000178568 NA ERBB4 v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian) 2066 ENSG00000178568
9  ENSG00000163630 NA SYNPR synaptoporin 132204 ENSG00000163630
10  ENSG00000166833 NA NAV2 neuron navigator 2 89797 ENSG00000166833
11  ENSG00000178996 NA SNX18 sorting nexin 18 112574 ENSG00000178996
12  ENSG00000197467 NA COL13A1 collagen, type XIII, alpha 1 1305 ENSG00000197467
13  ENSG00000108576 NA SLC6A4 solute carrier family 6 (neurotransmitter transporter, serotonin), member 4 6532 ENSG00000108576
14  ENSG00000135914 NA HTR2B 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled 3357 ENSG00000135914
15  ENSG00000184672 NA RALYL RALY RNA binding protein-like 138046 ENSG00000184672
16  ENSG00000157168 NA NRG1 neuregulin 1 3084 ENSG00000157168
17  ENSG00000206561 NA COLQ collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase 8292 ENSG00000206561


Database:Transcription Target       Name:hsa_GGGCGGR_V$SP1_Q6       ID:DB_ID:2452
C=2891; O=23; E=6.37; R=3.61; rawP=5.40e-08; adjP=4.20e-06
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000164040 NA PGRMC2 progesterone receptor membrane component 2 10424 ENSG00000164040
2  ENSG00000091428 NA RAPGEF4 Rap guanine nucleotide exchange factor (GEF) 4 11069 ENSG00000091428
3  ENSG00000244405 NA ETV5 ets variant 5 2119 ENSG00000244405
4  ENSG00000205038 NA PKHD1L1 polycystic kidney and hepatic disease 1 (autosomal recessive)-like 1 93035 ENSG00000205038
5  ENSG00000159212 NA CLIC6 chloride intracellular channel 6 54102 ENSG00000159212
6  ENSG00000198732 NA SMOC1 SPARC related modular calcium binding 1 64093 ENSG00000198732
7  ENSG00000131188 NA PRR7 proline rich 7 (synaptic) 80758 ENSG00000131188
8  ENSG00000178568 NA ERBB4 v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian) 2066 ENSG00000178568
9  ENSG00000132383 NA RPA1 replication protein A1, 70kDa 6117 ENSG00000132383
10  ENSG00000177508 NA IRX3 iroquois homeobox 3 79191 ENSG00000177508
11  ENSG00000155011 NA DKK2 dickkopf 2 homolog (Xenopus laevis) 27123 ENSG00000155011
12  ENSG00000196547 NA MAN2A2 mannosidase, alpha, class 2A, member 2 4122 ENSG00000196547
13  ENSG00000176842 NA IRX5 iroquois homeobox 5 10265 ENSG00000176842
14  ENSG00000121900 NA TMEM54 transmembrane protein 54 113452 ENSG00000121900
15  ENSG00000167323 NA STIM1 stromal interaction molecule 1 6786 ENSG00000167323
16  ENSG00000061918 NA GUCY1B3 guanylate cyclase 1, soluble, beta 3 2983 ENSG00000061918
17  ENSG00000075945 NA KIFAP3 kinesin-associated protein 3 22920 ENSG00000075945
18  ENSG00000065320 NA NTN1 netrin 1 9423 ENSG00000065320
19  ENSG00000107731 NA UNC5B unc-5 homolog B (C. elegans) 219699 ENSG00000107731
20  ENSG00000175832 NA ETV4 ets variant 4 2118 ENSG00000175832
21  ENSG00000186532 NA SMYD4 SET and MYND domain containing 4 114826 ENSG00000186532
22  ENSG00000159314 NA ARHGAP27 Rho GTPase activating protein 27 201176 ENSG00000159314
23  ENSG00000079689 NA SCGN secretagogin, EF-hand calcium binding protein 10590 ENSG00000079689


Database:Transcription Target       Name:hsa_V$CRX_Q4       ID:DB_ID:2173
C=266; O=8; E=0.59; R=13.65; rawP=1.44e-07; adjP=8.96e-06
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000106536 NA POU6F2 POU class 6 homeobox 2 11281 ENSG00000106536
2  ENSG00000164741 NA DLC1 deleted in liver cancer 1 10395 ENSG00000164741
3  ENSG00000176842 NA IRX5 iroquois homeobox 5 10265 ENSG00000176842
4  ENSG00000178031 NA ADAMTSL1 ADAMTS-like 1 92949 ENSG00000178031
5  ENSG00000148200 NA NR6A1 nuclear receptor subfamily 6, group A, member 1 2649 ENSG00000148200
6  ENSG00000178568 NA ERBB4 v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian) 2066 ENSG00000178568
7  ENSG00000244405 NA ETV5 ets variant 5 2119 ENSG00000244405
8  ENSG00000143869 NA GDF7 growth differentiation factor 7 151449 ENSG00000143869


Database:Transcription Target       Name:hsa_GATTGGY_V$NFY_Q6_01       ID:DB_ID:2440
C=1141; O=13; E=2.51; R=5.17; rawP=1.36e-06; adjP=7.05e-05
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000135119 NA RNFT2 ring finger protein, transmembrane 2 84900 ENSG00000135119
2  ENSG00000163630 NA SYNPR synaptoporin 132204 ENSG00000163630
3  ENSG00000166833 NA NAV2 neuron navigator 2 89797 ENSG00000166833
4  ENSG00000178031 NA ADAMTSL1 ADAMTS-like 1 92949 ENSG00000178031
5  ENSG00000167323 NA STIM1 stromal interaction molecule 1 6786 ENSG00000167323
6  ENSG00000244405 NA ETV5 ets variant 5 2119 ENSG00000244405
7  ENSG00000120057 NA SFRP5 secreted frizzled-related protein 5 6425 ENSG00000120057
8  ENSG00000166016 NA ABTB2 ankyrin repeat and BTB (POZ) domain containing 2 25841 ENSG00000166016
9  ENSG00000117595 NA IRF6 interferon regulatory factor 6 3664 ENSG00000117595
10  ENSG00000175832 NA ETV4 ets variant 4 2118 ENSG00000175832
11  ENSG00000206561 NA COLQ collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase 8292 ENSG00000206561
12  ENSG00000183091 NA NEB nebulin 4703 ENSG00000183091
13  ENSG00000177508 NA IRX3 iroquois homeobox 3 79191 ENSG00000177508


Database:Transcription Target       Name:hsa_V$OCT1_06       ID:DB_ID:1962
C=264; O=7; E=0.58; R=12.04; rawP=2.08e-06; adjP=7.19e-05
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000162670 NA FAM5C family with sequence similarity 5, member C 339479 ENSG00000162670
2  ENSG00000147606 NA SLC26A7 solute carrier family 26, member 7 115111 ENSG00000147606
3  ENSG00000164270 NA HTR4 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled 3360 ENSG00000164270
4  ENSG00000178568 NA ERBB4 v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian) 2066 ENSG00000178568
5  ENSG00000184672 NA RALYL RALY RNA binding protein-like 138046 ENSG00000184672
6  ENSG00000177508 NA IRX3 iroquois homeobox 3 79191 ENSG00000177508
7  ENSG00000076356 NA PLXNA2 plexin A2 5362 ENSG00000076356


Database:Transcription Target       Name:hsa_TGACAGNY_V$MEIS1_01       ID:DB_ID:2432
C=819; O=11; E=1.80; R=6.10; rawP=1.99e-06; adjP=7.19e-05
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000143171 NA RXRG retinoid X receptor, gamma 6258 ENSG00000143171
2  ENSG00000166833 NA NAV2 neuron navigator 2 89797 ENSG00000166833
3  ENSG00000147606 NA SLC26A7 solute carrier family 26, member 7 115111 ENSG00000147606
4  ENSG00000175206 NA NPPA natriuretic peptide A 4878 ENSG00000175206
5  ENSG00000076356 NA PLXNA2 plexin A2 5362 ENSG00000076356
6  ENSG00000075945 NA KIFAP3 kinesin-associated protein 3 22920 ENSG00000075945
7  ENSG00000166016 NA ABTB2 ankyrin repeat and BTB (POZ) domain containing 2 25841 ENSG00000166016
8  ENSG00000198732 NA SMOC1 SPARC related modular calcium binding 1 64093 ENSG00000198732
9  ENSG00000157168 NA NRG1 neuregulin 1 3084 ENSG00000157168
10  ENSG00000108556 NA CHRNE cholinergic receptor, nicotinic, epsilon (muscle) 1145 ENSG00000108556
11  ENSG00000079689 NA SCGN secretagogin, EF-hand calcium binding protein 10590 ENSG00000079689


Database:Transcription Target       Name:hsa_YATTNATC_UNKNOWN       ID:DB_ID:2385
C=370; O=8; E=0.82; R=9.82; rawP=1.73e-06; adjP=7.19e-05
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000164741 NA DLC1 deleted in liver cancer 1 10395 ENSG00000164741
2  ENSG00000106536 NA POU6F2 POU class 6 homeobox 2 11281 ENSG00000106536
3  ENSG00000162670 NA FAM5C family with sequence similarity 5, member C 339479 ENSG00000162670
4  ENSG00000183091 NA NEB nebulin 4703 ENSG00000183091
5  ENSG00000206561 NA COLQ collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase 8292 ENSG00000206561
6  ENSG00000112394 NA SLC16A10 solute carrier family 16, member 10 (aromatic amino acid transporter) 117247 ENSG00000112394
7  ENSG00000177508 NA IRX3 iroquois homeobox 3 79191 ENSG00000177508
8  ENSG00000143869 NA GDF7 growth differentiation factor 7 151449 ENSG00000143869


Database:Transcription Target       Name:hsa_TGGAAA_V$NFAT_Q4_01       ID:DB_ID:2437
C=1871; O=16; E=4.12; R=3.88; rawP=3.18e-06; adjP=9.89e-05
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000155011 NA DKK2 dickkopf 2 homolog (Xenopus laevis) 27123 ENSG00000155011
2  ENSG00000221866 NA PLXNA4 plexin A4 91584 ENSG00000221866
3  ENSG00000176842 NA IRX5 iroquois homeobox 5 10265 ENSG00000176842
4  ENSG00000164040 NA PGRMC2 progesterone receptor membrane component 2 10424 ENSG00000164040
5  ENSG00000102010 NA BMX BMX non-receptor tyrosine kinase 660 ENSG00000102010
6  ENSG00000178031 NA ADAMTSL1 ADAMTS-like 1 92949 ENSG00000178031
7  ENSG00000147606 NA SLC26A7 solute carrier family 26, member 7 115111 ENSG00000147606
8  ENSG00000148200 NA NR6A1 nuclear receptor subfamily 6, group A, member 1 2649 ENSG00000148200
9  ENSG00000061918 NA GUCY1B3 guanylate cyclase 1, soluble, beta 3 2983 ENSG00000061918
10  ENSG00000244405 NA ETV5 ets variant 5 2119 ENSG00000244405
11  ENSG00000184672 NA RALYL RALY RNA binding protein-like 138046 ENSG00000184672
12  ENSG00000164741 NA DLC1 deleted in liver cancer 1 10395 ENSG00000164741
13  ENSG00000157168 NA NRG1 neuregulin 1 3084 ENSG00000157168
14  ENSG00000162670 NA FAM5C family with sequence similarity 5, member C 339479 ENSG00000162670
15  ENSG00000206561 NA COLQ collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase 8292 ENSG00000206561
16  ENSG00000178568 NA ERBB4 v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian) 2066 ENSG00000178568




WebGestalt is currently developed and maintained by Jing Wang and Bing Zhang at the Zhang Lab. Other people who have made significant contribution to the project include Dexter Duncan, Stefan Kirov, Zhiao Shi, and Jay Snoddy.

Funding credits: NIH/NIAAA (U01 AA016662, U01 AA013512); NIH/NIDA (P01 DA015027); NIH/NIMH (P50 MH078028, P50 MH096972); NIH/NCI (U24 CA159988); NIH/NIGMS (R01 GM088822).